NGFR Antibody
Referência OAEE00173
Tamanho : 0.1mg(C100)
Marca : Aviva Systems Biology
Contactar o distribuidor local :
Telefone : +1 850 650 7790
| Datasheets/Manuals | Printable datasheet for NGFR Antibody (OAEE00173) (OAEE00173) |
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| Predicted Species Reactivity | Cat|Ferret|Human|Non-human Primate|Rabbit |
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| Product Format | Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide |
| Clonality | Monoclonal |
| Clone | NGFR5 |
| Isotype | IgG1 |
| Host | Mouse |
| Application | FC, IF, IHC, IP, RIA, WB |
| Reconstitution and Storage | 2°C to 8°C |
| Immunogen | Purified CD271 protein isolated from human melanoma cell line A875 |
| Purification | Purified |
| Concentration | 1 mg/ml |
| Specificity | The mouse monoclonal antibody NGFR5 (originally C34C) recognizes CD271/NGFR, a 75 kDa transmembrane glycoprotein of the TNFR superfamily. The epitope is localized within ammino acids 1 - 160. |
| Formulation | Purified |
| Purity | > 95% (by SDS-PAGE) |
| Storage Buffer | Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4 |
| Reference | Alpers CE, Hudkins KL, Ferguson M, Johnson RJ, Schatteman GC, Bothwell M: Nerve growth factor receptor expression in fetal, mature, and diseased human kidneys. Lab Invest. 1993 Dec;69(6):703-13. Schatteman GC, Gibbs L, Lanahan AA, Claude P, Bothwell M: Expression of NGF receptor in the developing and adult primate central nervous system. J Neurosci. 1988 Mar;8(3):860-73. Schatteman GC, Gibbs L, Lanahan AA, Claude P, Bothwell M: Expression of NGF receptor in the developing and adult primate central nervous system. J Neurosci. 1988 Mar;8(3):860-73. Marano N, Dietzschold B, Earley JJ Jr, Schatteman G, Thompson S, Grob P, Ross AH, Bothwell M, Atkinson BF, Koprowski H: Purification and amino terminal sequencing of human melanoma nerve growth factor receptor. J Neurochem. 1987 Jan;48(1):225-32. Thompson SJ, Schatteman GC, Gown AM, Bothwell M: A monoclonal antibody against nerve growth factor receptor. Immunohistochemical analysis of normal and neoplastic human tissue. Am J Clin Pathol. 1989 Oct;92(4):415-23. |
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| Gene Symbol | NGFR |
| Gene Full Name | nerve growth factor receptor |
| Alias Symbols | CD271;Gp80-LNGFR;low affinity neurotrophin receptor p75NTR;low-affinity nerve growth factor receptor;NGF receptor;p75 ICD;p75(NTR);p75NTR;TNFR superfamily, member 16;TNFRSF16;tumor necrosis factor receptor superfamily member 16. |
| NCBI Gene Id | 4804 |
| Protein Name | Tumor necrosis factor receptor superfamily member 16 |
| Description of Target | Plays a role in the regulation of the translocation of GLUT4 to the cell surface in adipocytes and skeletal muscle cells in response to insulin, probably by regulating RAB31 activity, and thereby contributes to the regulation of insulin-dependent glucose uptake (By similarity). Low affinity receptor which can bind to NGF, BDNF, NT-3, and NT-4. Can mediate cell survival as well as cell death of neural cells. Necessary for the circadian oscillation of the clock genes ARNTL/BMAL1, PER1, PER2 and NR1D1 in the suprachiasmatic nucleus (SCN) of the brain and in liver and of the genes involved in glucose and lipid metabolism in the liver. |
| Uniprot ID | P08138 |
| Protein Accession # | NP_002498.1 |
| Nucleotide Accession # | NM_002507.3 |
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What is the species homology for "NGFR Antibody (OAEE00173)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Cat|Ferret|Human|Non-human Primate|Rabbit".
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How long will it take to receive "NGFR Antibody (OAEE00173)"?
This item is available "Domestic: within 1-2 week delivery | International: 1-2 weeks".
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What buffer format is "NGFR Antibody (OAEE00173)" provided in?
This item is provided in "Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "NGFR Antibody (OAEE00173)"?
This target may also be called "CD271;Gp80-LNGFR;low affinity neurotrophin receptor p75NTR;low-affinity nerve growth factor receptor;NGF receptor;p75 ICD;p75(NTR);p75NTR;TNFR superfamily, member 16;TNFRSF16;tumor necrosis factor receptor superfamily member 16." in publications.
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What is the shipping cost for "NGFR Antibody (OAEE00173)"?
The shipping cost for this item is within the US. Please contact us for specific shipping for international orders.
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What is the guarantee for "NGFR Antibody (OAEE00173)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "NGFR Antibody (OAEE00173)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "NGFR Antibody (OAEE00173)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "NGFR"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "NGFR"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "NGFR"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "NGFR"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "NGFR"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "NGFR"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.