PAX2 Antibody - middle region : Biotin
Referência P100859_T100-Biotin
Tamanho : 100ul
Marca : Aviva Systems Biology
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PAX2 Antibody - middle region (P100859_T100)
| Datasheets/Manuals | Printable datasheet for anti-PAX2 (P100859_T100) antibody |
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| Tested Species Reactivity | Human |
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| Predicted Species Reactivity | Human, Mouse, Rat, Cow, Dog, Guinea Pig, Rabbit, Sheep, Zebrafish |
| Product Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Clonality | Polyclonal |
| Host | Rabbit |
| Application | IHC, WB |
| Reconstitution and Storage | For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Immunogen | The immunogen is a synthetic peptide directed towards the middle region of human PAX2 |
| Purification | Protein A purified |
| Predicted Homology Based on Immunogen Sequence | Cow: 100%; Dog: 100%; Guinea Pig: 100%; Human: 100%; Mouse: 92%; Rabbit: 100%; Rat: 92%; Sheep: 100%; Zebrafish: 100% |
| Peptide Sequence | Synthetic peptide located within the following region: VSSASNDPVGSYSINGILGIPRSNGEKRKRDEDVSEGSVPNGDSQSGVDS |
| Concentration | 1.0 mg/ml |
| Blocking Peptide | For anti-PAX2 (P100859_T100) antibody is Catalog # AAP31220 (Previous Catalog # AAPP01965) |
| Reference | Muratovska, A., et al., (2003) Oncogene 22 (39), 7989-7997. |
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| Gene Symbol | PAX2 |
| Gene Full Name | Paired box 2 |
| Alias Symbols | FSGS7, PAPRS |
| NCBI Gene Id | 5076 |
| Protein Name | Paired box protein Pax-2 |
| Description of Target | PAX2 encodes paired box gene 2, one of many human homologues of the Drosophila melanogaster gene prd. The central feature of this transcription factor gene family is the conserved DNA-binding paired box domain. PAX2 is believed to be a target of transcriptional supression by the tumor supressor gene WT1. Mutations within PAX2 have been shown to result in optic nerve colobomas and renal hypoplasia. |
| Uniprot ID | Q02962 |
| Protein Accession # | NP_003979 |
| Nucleotide Accession # | NM_003988 |
| Protein Size (# AA) | 417 |
| Molecular Weight | 45kDa |
| Protein Interactions | BBS7; BBS4; BBS2; BBS1; RB1; BRCA1; SFRP2; PAXIP1; WT1; MAPK8IP1; MAPK8; ID2; |
