PE Anti-Rat CD45 Monoclonal Antibody (Clone: OX-1)
Referência E-AB-F1227D-50
Tamanho : 50Tests
Marca : Elabscience
Alternate Names | LCALy-5T200, Leukocyte common antigen, Ptprc, Receptor-type tyrosine-protein phosphatase C |
Clone No | |
Leadtime | Order now, ship in 3 days |
Background | CD45 is a 180-220 kD protein also known as leukocyte common antigen (LCA). It is a protein tyrosine phosphatase with multiple isoforms differing as a result of alternative splicing of the extracellular domain and glycosylation. CD45 is expressed on all hematopoietic cells except erythrocytes and platelets; isoform expression depends on cell type, activation state, and cell maturation. CD45 functions in signal transduction through T and B cell antigen receptors. CD45 has been shown to interact with various proteins including galectin-1, CD2, CD3, and CD4. The OX-1 antibody has been shown to partially inhibit NK cell-mediated lysis of syngeneic tumor cells in vitro. |
Abbre | CD45 |
Swissprot | |
Host | Mouse |
Reactivity | Rat |
Clonality | Monoclonal |
Isotype | Mouse IgG1, κ |
Isotype Control | E-AB-F09792D |
Applications | FCM |
Research Areas | Cell Biology;Immunology;Inhibitory Molecules;Neuroscience;Neuroscience Cell Markers |
Cellular Localization | Membrane |
Form | Liquid |
Concentration | 5 μL/Test |
Conjugation | PE |
Conjugation Information | PE is designed to be excited by the Blue (488 nm), Green (532 nm) and Yellow-Green (561 nm) lasers and detected using an optical filter centered near 575 nm (e.g., a 585/42 nm bandpass filter). |
Spectrum | |
Storage Buffer | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant. |
Storage | This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze. |
Expiration Date | 12 months |
Shipping | Ice bag |
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