Orally active biphosphonate that inhibits farnesyl diphosphate (FPP) synthase. Exhibits antiproliferative and proapoptotic activity in numerous tumor cell lines and inhibits osteoclast-mediated bone reabsorption in vivo.
Chemical Properties
Physical Appearance
A solid
Storage
Store at -20°C
M.Wt
305.09
Cas No.
115436-72-1
Formula
C7H10NNaO7P2
Solubility
insoluble in EtOH; insoluble in DMSO; ≥10.17 mg/mL in H2O with gentle warming