ALS13608 | TGF-Beta Antibody (clone TB21) Clinisciences

Product Information
Application Applications Legend: WB=Western Blot IHC=Immunohistochemistry IHC-P=Immunohistochemistry (Paraffin-embedded Sections) IHC-F=Immunohistochemistry (Frozen Sections) IF=Immunofluorescence FC=Flow Cytopmetry IC=Immunochemistry ICC=Immunocytochemistry E=ELISA IP=Immunoprecipitation DB=Dot Blot CHIP=Chromatin Immunoprecipitation FA=Fluorescence Assay IEM=Immuno electron microscopy EIA=Enzyme Immunoassay	WB, IHC-P, E, IHC-F, Neut, FuncS
Primary Accession	P01137
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Clone Names	TB21
Calculated MW	44325 Da
Dilution	IHC-P (10 µg/ml)

Additional Information
Gene ID	7040
Other Names	Transforming growth factor beta-1, TGF-beta-1, Latency-associated peptide, LAP, TGFB1, TGFB
Target/Specificity	Recognizes both human platelet-derived and recombinant TGF-beta.
Reconstitution & Storage	Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.
Precautions	TGF-Beta Antibody (clone TB21) is for research use only and not for use in diagnostic or therapeutic procedures.

Protein Information
Name	TGFB1 (HGNC:11766)
Synonyms	TGFB
Function	Transforming growth factor beta-1 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-1 (TGF-beta-1) chains, which constitute the regulatory and active subunit of TGF-beta-1, respectively.
Cellular Location	[Latency-associated peptide]: Secreted, extracellular space, extracellular matrix
Tissue Location	Highly expressed in bone (PubMed:11746498, PubMed:17827158). Abundantly expressed in articular cartilage and chondrocytes and is increased in osteoarthritis (OA) (PubMed:11746498, PubMed:17827158). Colocalizes with ASPN in chondrocytes within OA lesions of articular cartilage (PubMed:17827158)
Volume	250 µl

TGF-Beta Antibody (clone TB21)