Ubiquitin (P4D1)
Referência sc-8017
Tamanho : 200µg/ml
Marca : Santa Cruz Biotechnology
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Anticorps Ubiquitin (P4D1): sc-8017
- L'anticorps Ubiquitin P4D1 est un monoclonal IgG1 κ L'Anticorps Ubiquitin, cité dans 3.261 publications, fourni en 200 µg/ml
- dirigé contre les acides aminés 1-76 représentant la protéine totale Ubiquitin de bovine
- L'Anticorps Ubiquitin (P4D1) est recommandé pour la détection de Ubiquitin, poly-ubiquitinated and ubiquitinated proteins d'origine mouse, rat, human et Drosophila par WB, IP, IF, IHC(P), FCM et ELISA
- L'Anticorps Ubiquitin (P4D1) est disponible conjugué à l'agarose pour IP; à l'HRP pour WB, IHC(P) et ELISA; et soit à la phycoerythrin ou FITC pour IF, IHC(P) et FCM
- aussi disponible conjugué à l'Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 ou Alexa Fluor® 647 pour WB (RGB), IF, IHC(P) et FCM
- aussi disponible conjugué à l'Alexa Fluor® 680 ou Alexa Fluor® 790 pour WB (NIR), IF et FCM
- disponible conjugué à la biotine pour WB, IHC(P) et ELISA; et à l'Alexa Fluor® 405 pour IF, IHC(P) et FCM
- aussi disponible conjugué à l'Alexa Fluor® 405 pour IF, IHC(P) et FCM
- m-IgG Fc BP-HRP et 1 BP-HRP">m-IgG1 BP-HRP sont les réactifs secondaires recommandés pour la détection de l'anticorps Ubiquitin (P4D1) pour des applications de WB and IHC(P). Ces réactifs sont maintenant proposés en kit avec l'anticorps Ubiquitin (P4D1) ().
ACCÈS RAPIDE AUX LIENS
, Ub+1 et USPL1
Ubiquitin Antibody (P4D1) is an IgG1 κ mouse monoclonal Ubiquitin antibody (also designated Ub antibody) that detects the Ubiquitin protein of mouse, rat, human and Drosophila melanogaster origin by WB, IP, IF, IHC(P), FCM and ELISA. Ubiquitin Antibody (P4D1) is available as both the non-conjugated anti-Ubiquitin antibody form, as well as multiple conjugated forms of anti-Ubiquitin antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. Ubiquitin (Ub) is among the most phylogenetically conserved proteins known. The primary function of Ubiquitin is to clear abnormal, foreign and improperly folded proteins by targeting them for degradation by the 26S Proteosome. This small, 76 amino acid protein can be covalently attached to cellular proteins via an isopeptide linkage between the carboxy terminal group of Ubiquitin and lysine amino groups on the acceptor protein. For proteolysis to occur, Ubiquitin oligomers must be assembled. Ubiquitin chains on proteolytic substrates are commonly found to have an isopeptide bridge between Lys 48 of one Ubiquitin molecule and the carboxy-terminus of a neighboring Ubiquitin molecule. Ubiquitin also plays a role in regulating signal transduction cascades through the elimination inhibitory proteins, such as IκB-α and p27.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
References:
- Ubiquitin, proteasomes, and the regulation of intracellular protein degradation. | Hochstrasser, M. 1995. Curr Opin Cell Biol. 7: 215-23. PMID: 7612274
- Role of the ubiquitin-proteasome pathway in regulating abundance of the cyclin-dependent kinase inhibitor p27. | Pagano, M., et al. 1995. Science. 269: 682-5. PMID: 7624798
- Ubiquitin and the enigma of intracellular protein degradation. | Jennissen, HP. 1995. Eur J Biochem. 231: 1-30. PMID: 7628459
- Ubiquitin in homeostasis, development and disease. | Muller, S. and Schwartz, LM. 1995. Bioessays. 17: 677-84. PMID: 7661849
- The ubiquitin-proteasome proteolytic pathway. | Ciechanover, A. 1994. Cell. 79: 13-21. PMID: 7923371
- The ubiquitin-mediated proteolytic pathway: mechanisms of recognition of the proteolytic substrate and involvement in the degradation of native cellular proteins. | Ciechanover, A. and Schwartz, AL. 1994. FASEB J. 8: 182-91. PMID: 8119489
- Protein degradation or regulation: Ub the judge. | Hochstrasser, M. 1996. Cell. 84: 813-5. PMID: 8601303
- Site-specific phosphorylation of IkappaBalpha by a novel ubiquitination-dependent protein kinase activity. | Chen, ZJ., et al. 1996. Cell. 84: 853-62. PMID: 8601309
Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz® conjugates which eliminates the need for a secondary antibody.
Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-Ubiquitin Antibody (P4D1) has 3,237 citations in a variety of scientific publications.
Primary antibodies like Anti-Ubiquitin Antibody (P4D1) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.
Informations pour la commande
Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps Ubiquitin (P4D1) | sc-8017 | 200 µg/ml | .00 | |||
Ubiquitin (P4D1): m-IgG Fc BP-HRP Kit | sc-526508 | 200 µg Ab; 10 µg BP | .00 | |||
Ubiquitin (P4D1): m-IgG1 BP-HRP Kit | sc-531881 | 200 µg Ab; 20 µg BP | .00 | |||
Anticorps Ubiquitin (P4D1) AC | sc-8017 AC | 500 µg/ml, 25% agarose | .00 | |||
Anticorps Ubiquitin (P4D1) HRP | sc-8017 HRP | 200 µg/ml | .00 | |||
Anticorps Ubiquitin (P4D1) FITC | sc-8017 FITC | 200 µg/ml | .00 | |||
Anticorps Ubiquitin (P4D1) PE | sc-8017 PE | 200 µg/ml | .00 | |||
Anticorps Ubiquitin (P4D1) Alexa Fluor® 488 | sc-8017 AF488 | 200 µg/ml | .00 | |||
Anticorps Ubiquitin (P4D1) Alexa Fluor® 546 | sc-8017 AF546 | 200 µg/ml | .00 | |||
Anticorps Ubiquitin (P4D1) Alexa Fluor® 594 | sc-8017 AF594 | 200 µg/ml | .00 | |||
Anticorps Ubiquitin (P4D1) Alexa Fluor® 647 | sc-8017 AF647 | 200 µg/ml | .00 | |||
Anticorps Ubiquitin (P4D1) Alexa Fluor® 680 | sc-8017 AF680 | 200 µg/ml | .00 | |||
Anticorps Ubiquitin (P4D1) Alexa Fluor® 790 | sc-8017 AF790 | 200 µg/ml | .00 | |||
Anticorps Ubiquitin (P4D1) B | sc-8017 B | 200 µg/ml | .00 | |||
Anticorps Ubiquitin (P4D1) Alexa Fluor® 405 | sc-8017 AF405 | 200 µg/ml | .00 |
will lactacystin always increase the ubiquitin staining in all the cells, as you have posted a figure in the datasheet about HeLA cells?
We want to use P4D1 antibodies for Immunohistochemistry (IHC), Can you please recommend us some published papers where they have used these antibodies for IHC?
How good is this antibody in detecting mono-ubiquitinated protein in an immunoblot?
hi, I want to use Ubiquitin (P4D1) antibody for western, what concentration do you suggest? Thanks
How good is this antibody for immunostaining?
这个抗体的分子量是确定的9KD吗?IP过的蛋白敷完这个抗体也是在9KD有条带吗?
Hello I would like 2 quotes for this Ub Antibody (P4D1): sc-8017 Uncojugated and HRP conjugated, they are supposed to have the same . I belong to a non-profit institution (we are affiliated to Montreal University), consider it,please
IP实验的推荐稀释浓度是多少?
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