Vorinostat (SAHA, MK0683) [149647-78-9]
Referência AOB6083-10
Tamanho : 10mg
Marca : AOBIOUS
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Data sheet
| Molecular Formula | C14H20N2O4 |
| Molecular Weight | 264.3 |
| CAS Numbers | 149647-78-9 |
| Storage Condition | 0°C (short term), -20°C (long term), desiccated |
| Solubility | DMSO |
| Purity | 99% (HPLC) |
| Synonym | N1-hydroxy-N8-phenyl-octanediamide |
| IUPAC/Chemical Name | SAHA; Suberoylanilide Hydroxamic Acid Vorinostat |
| InChl Key | WAEXFXRVDQXREF-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C14H20N2O3/c17-13(15-12-8-4-3-5-9-12)10-6-1-2-7-11-14(18)16-19/h3-5,8-9,19H,1-2,6-7,10-11H2,(H,15,17)(H,16,18) |
| SMILES Code | ONC(=O)CCCCCCC(=O)Nc1ccccc1 |
| References | 1) Marks, P.A., and Breslow, R. Dimethyl sulfoxide to vorinostat: Development of this histone deacetylase inhibitor as an anticancer drug. Nat. Biotechnol. 25(1), 84-90 (2007). |
More info
A small molecule inhibitor of histone deacetylase (HDAC)