Angene
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A Angene está empenhada em fornecer produtos químicos de qualidade para utilização em investigação e desenvolvimento e fabrico comercial. A Angene oferece mais de 100.000 produtos, incluindo reagentes de laboratório, blocos de construção, intermediários, produtos a granel, agro-químicos, ingredientes naturais e ingredientes farmacêuticos activos (APIs). Para além dos mais de 100.000 produtos, a Angene oferece síntese personalizada de produtos químicos que não estão disponíveis comercialmente.
Sítio Web: www.angenechemical.com
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![SARS-CoV-2 - Deferoxamine - Therapeutic Candidates](https://www.clinisciences.com/pt/upload/thumbs/therapeutic-covid-19-k6n3ra-7cd06d.jpg)
SARS-CoV-2 - Deferoxamine - Therapeutic Candidates
Deferoxamine (or Desferal) is a linear bacterial siderophore and chelating agent for trivalent cations. Deferoxamine is capable of binding free iron from plasma or cells to form the ferrioxamine complex. Due to its properties, deferoxamine is used as a first-line treatment for iron overload. Desferal is prescribed for various pathologies such as primary hemochromatosis, secondary hemosiderosis, acute martial intoxication, aluminum poisoning.
Deferoxamine has been included in some clinical studies to develop a treatment for COVID-19 caused by the SARS-CoV-2 coronavirus. Indeed, studies have shown that the replication of some RNA viruses, such as HIV-1 or cytomegalovirus, can be influenced by iron. Deferoxamine was able to inhibit viral replication in cells in vitro. For this reason, deferoxamine is being tested as part of the development of a treatment for COVID-19.
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