Reagentes e instrumentos para imunologia, biologia celular e biologia molecular.
 

PhytoTechnology Labs


PhytoTechnology Laboratories focusses on providing products for plant tissue culture research and plant production. PhytoTech's products are focused on plant tissue culture but we also carry lines of products for plant molecular biology, phycologoy and seed testing applications. PhytoTechnology Laboratories is an industry leader in the manufacture of plant tissue culture media and we carry more than 150 stock formulations of media, and can produce custom formulations of your tissue culture media formulations. 

Discover some products :

  • Media optimization kit helps you develop an optimal media formulation for your crops. 
  • A new line of pre-poured, ready-to-use plant media in culture tubes, called PhytoReady. 
  • Two excellent new plastic culture vessels: the PTL-100 and the PT-12 Culture Jar. 


 
> PhytoTechnology Labs > Produtos para investigação > COVID-19 > SARS-CoV-2 - Candidatos terapêuticos para investigação e desenvolvimento > SARS-CoV-2 - Colchicine - Therapeutic Candidates
SARS-CoV-2 - Colchicine - Therapeutic Candidates

SARS-CoV-2 - Colchicine - Therapeutic Candidates


Colchicine is an anti-inflammatory drug used in rheumatology and particularly for the treatment of gouty arthritis or gout. Colchicine is also used in the treatment of other pathologies such as chronic atrophic polychondritis or acute pericarditis after failure of aspirin. 
Studies have shown that SARS-CoVs activate NLRP3 inflammasomes, intracytoplasmic particles that stimulate the release of pro-inflammatory cytokines. In particular, colchicine is believed to inhibit the assembly of the NLRP3 inflammasome and thus the release of cytokines, in particular interleukin-1 beta and interleukin-6. Colchicine is believed to inhibit certain functions of the inflammasome, a component of the immune system that plays a role in triggering cytokine shock and the associated inflammatory cascade. Targeting the inflammatory response with colchicine may therefore reduce complications related to Covid-19 in adults at risk or with signs of inflammatory storm. Three studies are currently underway to investigate the effects of colchicine on Covid-19, the largest, called COLCORONA, involves 6000 patients in Canada.

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