Schaedler's broth is excellent for primary isolation of anaerobes, for blood cultures and other clinical materials. It is useful for the determination of the minimum inhibitory concentration (MIC) of antimicrobials used in susceptibility testing. The solid medium is not used for susceptibility testing because there is no effective agreement between the drug concentration and the diameters of the inhibition zones that are observed when the solid medium is used. Schaedler's broth is a highly nutritious medium due to the use of tryptone, protein peptone, soy peptone and yeast extract.