Citric acid cycle
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The citric acid cycle
is a series of chemical reactions used by all aerobic organisms to
generate energy through the oxidation of acetyl-CoA derived from
carbohydrates, fats and proteins into carbon dioxide and chemical
energy in the form of ATP. In addition, the cycle provides precursors
of certain amino acids as well as the reducing agent NADH.
In eukaryotic cells, the citric acid
cycle occurs in the matrix of the mitochondrion.
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Oxaloacetate
Oxaloacetate reacts with Acetyl-CoA to form citrate. Please find assay kits for oxaloacetate.
Acetyl-CoA
The main function of Acetyl-CoA is to deliver the acetyl group to be oxidized for energy production. Please find assay kits for Acetyl-CoA.
Citrate synthase
Citrate synthase catalyzes the condensation reaction of Acetyl-CoA and oxaloacetate to form citrate. Please find for citrate synthase: antibodies, cDNA clones, ELISA kits, peptides, blocking peptides, RNAi, assay kits.
Citrate
Please find assay kits for citrate.
Aconitase
Aconitase catalyses the isomerization of citrate to isocitrate via cis-aconitate. Please find for aconitase: antibodies, peptides, cDNA clones, ELISA kits, blocking peptides, assay kits.
Isocitrate
Please find assay kits for isocitrate.
Isocitrate dehydrogenase
Isocitrate dehydrogenase catalyses the oxidative decarboxylation of isocitrate producing alpha-ketoglutarate. Please find for isocitrate dehydrogenase: cDNA clones, antibodies, peptides, ELISA kits, assay kits.
Alpha-ketoglutarate
Please find assay kits for alpha-ketoglutarate.
Alpha-ketoglutarate dehydrogenase
Alpha-ketoglutarate dehydrogenase catalyzes decarboxylation of alpha-ketoglutarate to produce succinyl-CoA. Please find for alpha-ketoglutarate dehydrogenase: cDNA clones, assay kits, antibodies, peptides, ELISA kits.
Succinyl-CoA synthetase
Succinyl-CoA synthetase catalyzes the formation of succinate from succinyl-CoA. Please find assay kits for Succinyl-CoA synthetase.
Succinate
Please find assay kits for succinate.
Succinate dehydrogenase
Succinate dehydrogenase catalyzes the oxidation of succinate to fumarate. Please find for succinate dehydrogenase: cDNA clones, antibodies, peptides, ELISA kits, assay kits.
Fumarate
Please find assay kits for fumarate.
Fumarase
Fumarase catalyzes the hydratation of fumarate to malate. Please find for fumarase: antibodies, peptides, ELISA kits, blocking peptides, assay kits.
Malate
Please find assay kits for malate.
Malate dehydrogenase
Malate dehydrogenase catalyzes the oxidation of malate to oxaloacetate. Please find for malate dehydrogenase: cDNA clones, peptides, antibodies, ELISA kits, assay kits, blocking peptides.