DNA/RNA
We offer a wide range of custom services for DNA/RNA synthesis, modification, design, purification, and analysis. Whether you need mRNA, primers, probes, genes, clones, shRNA, DNA arrays, or PCR/RT-PCR products, we have the expertise and the technology to meet your needs. Our DNA/RNA services include:
- mRNA synthesis: Custom mRNAs with various modifications at different scales and lengths.
- Primer synthesis: Primers for various applications with labels, spacers, or quenchers.
- Probe synthesis: Probes for various applications with fluorophores, quenchers, or linkers.
- Gene synthesis: Genes of any length and complexity with codon optimization, error correction, and cloning options.
- Clone modification: Existing clones with site-directed mutagenesis, insertion, deletion, or fusion.
- shRNA design and synthesis: shRNA molecules for gene silencing with vector and delivery options.
- DNA arrays: Custom DNA arrays with thousands of oligonucleotides on a single chip.
- DNA/RNA purification: DNA or RNA from various sources with high yield and quality.
- PCR/RT-PCR experiment: PCR or RT-PCR experiments with optimized protocols and reagents.
At Clinisciences we are more than just a service provider; we are your scientific partner, dedicated to advancing your research goals. With a commitment to quality, precision, and innovation, we invite you to explore the possibilities that our DNA/RNA services offer.
nanoCAR-T mRNA service
Non-viral chimeric antigen receptor (CAR)-T cells are gaining attention for their cancer-killing ability with reduced side effects. Traditional CAR-T cell engineering relies on lentivirus, which causes random chromosomal integration, permanent CAR expression, and adverse effects from persistent immunologic stimulation. To address these issues, mRNA-based CAR-T therapy offers a promising alternative by enabling temporary yet effective CAR expression in T cells.
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mRNA synthesis
We can custom synthesize your mRNAs.
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Primer synthesis
We can custom synthesize your primers. => Quote request
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Probe synthesis
We can custom synthesize your DNA probes for qPCR (MolecularBeacons/EasyBeacons ou TaqMan®/HydrolEasy probes) => Quote request
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Gene synthesis
We propose to produce a double-stranded DNA from your nucleotidic sequence. => Quote request
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Clone modification
We propose you to modify your clone according to your needs. => Quote request
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shRNA design and synthesis
We propose you to synthetize your shRNA. => Quote request
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DNA Arrays
We developed a standardized process for developing Custom Projects. => Quote request
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DNA/RNA purification
We perform your extractions and purifications of nucleic acids. => Quote request
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PCR/RT-PCR experiment
We perform your PCR and RT-PCR from the biological material that you supply or from the one we prepare or synthetized for you. => Quote request
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