Anti-HSP70 Monoclonal Antibody (Clone : C92F3A-5) - ATTO 488
Figure1 : Mouse Anti-Hsp70 Antibody [C92F3A-5]used in Immunohistochemistry (IHC) on Mouse colon carcinoma
Tamanho : 200ug
Figure1 : Mouse Anti-Hsp70 Antibody [C92F3A-5]used in Immunohistochemistry (IHC) on Mouse colon carcinoma
Amount : | 200 µg |
Isotype : | Mouse IgG |
Purification : | Protein G Purified |
Content : | PBS pH7.4, 50% glycerol, 0.1% sodium azide |
Storage condition : | Store the antibody at 4°C |
WB (1:1000), IHC (1:10000), ICC/IF (1:1000), FACS (1:1000); optimal dilutions for assays should be determined by the user.
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
Subcellular location: | Cytoplasm, Nucleus, Cytoplasm |
Post transnational modification: | In response to cellular stress, acetylated at Lys-77 by NA110 and then gradually deacetylated by HDAC4 at later stages. Acetylation enhances its chaperone activity and also determines whether it will function as a chaperone for protein refolding or degradation by controlling its binding to co-chaperones HOPX and STUB1. The acetylated form and the non-acetylated form bind to HOPX and STUB1 respectively. Acetylation also protects cells against various types of cellular stress. |
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