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> Anti-WNT1 antibody (301-350 aa)

Anti-WNT1 antibody (301-350 aa)

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Referência NB-22-6270-50

Tamanho : 50ug

Marca : Neo Biotech

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  • Western blot analysis of HT29 cells using Wnt-1 Polyclonal Antibody diluted at 1：1000. Secondary antibody was diluted at 1:20000
  • Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using WNT1 Antibody. The picture on the right is blocked with the synthesized peptide.
  • Western blot analysis of various cells using Wnt-1 Polyclonal Antibody diluted at 1：1000. Secondary antibody was diluted at 1:20000

General Info

Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Proto-oncogene Wnt-1 (301-350 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC 1:100-1:300
IF 1:200-1:1000
ELISA 1:10000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Information

Gene Symbol: WNT1
Gene ID: 7471
Uniprot ID: WNT1_HUMAN
Immunogen Region: 301-350 aa
Specificity: Wnt-1 Polyclonal Antibody detects endogenous levels of Wnt-1 protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human WNT1 at the amino acid range 301-350

Description

Function Ligand for members of the frizzled family of seven transmembrane receptors (Probable). Acts in the canonical Wnt signaling pathway by promoting beta-catenin-dependent transcriptional activation. In some developmental processes, is also a ligand for the coreceptor RYK, thus triggering Wnt signaling. Plays an essential role in the development of the embryonic brain and central nervous system (CNS). Has a role in osteoblast function, bone development and bone homeostasis.
Protein Name Proto-Oncogene Wnt-1
Proto-Oncogene Int-1 Homolog
Database Links Reactome: R-HSA-201681
Reactome: R-HSA-3238698
Reactome: R-HSA-373080
Reactome: R-HSA-381340
Reactome: R-HSA-4086400
Reactome: R-HSA-4641262
Cellular Localisation Secreted
Extracellular Space
Extracellular Matrix
Alternative Antibody Names Anti-Proto-Oncogene Wnt-1 antibody
Anti-Proto-Oncogene Int-1 Homolog antibody
Anti-WNT1 antibody
Anti-INT1 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance