BIX01294 hydrochloride [1392399-03-9]
Referência sc-293525B
Tamanho : 25mg
Marca : Santa Cruz Biotechnology
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BIX01294 hydrochloride (CAS 1392399-03-9)
ACCÈS RAPIDE AUX LIENS
BIX01294 hydrochloride (CAS 1392399-03-9) Références:
- A Unique Virulence Gene Occupies a Principal Position in Immune Evasion by the Malaria Parasite Plasmodium falciparum. | Ukaegbu, UE., et al. 2015. PLoS Genet. 11: e1005234. PMID: 25993442
- High-throughput screening yields several small-molecule inhibitors of repeat-associated non-AUG translation. | Green, KM., et al. 2019. J Biol Chem. 294: 18624-18638. PMID: 31649034
- Screening of an Epigenetic Drug Library Identifies 4-((hydroxyamino)carbonyl)-N-(2-hydroxyethyl)-N-Phenyl-Benzeneacetamide that Reduces Melanin Synthesis by Inhibiting Tyrosinase Activity Independently of Epigenetic Mechanisms. | Song, H., et al. 2020. Int J Mol Sci. 21: PMID: 32605171
- A Machine Learning Strategy for Drug Discovery Identifies Anti-Schistosomal Small Molecules. | Zorn, KM., et al. 2021. ACS Infect Dis. 7: 406-420. PMID: 33434015
- High-Throughput Mechanistic Screening of Epigenetic Compounds for the Potential Treatment of Meningiomas. | Tatman, PD., et al. 2021. J Clin Med. 10: PMID: 34300316
- Nanchangmycin regulates FYN, PTK2, and MAPK1/3 to control the fibrotic activity of human hepatic stellate cells. | Li, W., et al. 2022. Elife. 11: PMID: 35617485
Modulation Targets
Inhibitor of: G9a, and HDAC.État Physique :
Solid
Solubilité :
Soluble in water (20 mg/ml).
Stockage :
Store at -20° C
IC50 :
G9a HMTase: IC50 = 1.7 µM; HMTase G9a-like protein: IC50 = 38 µM; Histone-lysine N-methyltransferase, H3 lysine-9 specific 5: IC50 = 27 nM (human); Histone-lysine N-methyltransferase, H3 lysine-9 specific 3: IC50 = 110 nM (human)
WGK Allemagne :
3
PubChem CID :
46945860SMILES :
COC1=CC2N=C(N=C(NC3CCN(CC3)Cc3ccccc3)C2C=C1OC)N1CCCN(C)CC1
Télécharger la Fiche de Sécurité/ SDS (MSDS)
Région
EXEMPLE de Certificat d'Analyse (CoA)
BIX01294 hydrochloride | CAS 1392399-03-9 SAMPLE Certificate of AnalysisCERTIFICAT D'ANALYSE
Numéro de catalogue
Numéro de Lot
SAMPLE Certificate of Analysis (COA)
Test | Specification | Results |
---|---|---|
Identification (Infrared Spectrum) | Consistent with standard | Complies |
Identification (Mass Spectrometry - APCI) | MH+: 491.4 | 491.3 |
Purity (TLC) | ≥ 98% | 100.00%Rf: 0.64 |
λmax | 212, 247, 333, 346 nm | 213, 247, 332, 346 nm |
TEST CONDITIONS
TLC condition: Mob. Phase: Chloroform: Methanol: Water (65: 35: 8); Stationary Phase: Silica Gel; Visualized With: UV
Informations pour la commande
Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
BIX01294 hydrochloride, 1 mg | sc-293525 | 1 mg | .00 | |||
BIX01294 hydrochloride, 5 mg | sc-293525A | 5 mg | .00 | |||
BIX01294 hydrochloride, 25 mg | sc-293525B | 25 mg | .00 |