COMP Recombinant Protein
Referência OPCD02353-50UG
Tamanho : 50ug
Marca : Aviva Systems Biology
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| Datasheets/Manuals | Printable datasheet for COMP Recombinant Protein (OPCD02353) |
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| Predicted Species Reactivity | Mouse|Mus musculus |
|---|---|
| Product Format | Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose. |
| Host | E.coli |
| Conjugation | Unconjugated |
| Application | Ctrl (+), SDS-PAGE, WB |
| Additional Information | Endotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method) |
| :: | Residues: Thr40-Asn180 |
| Reconstitution and Storage | 2°C to 8°C|-80°C |
| Concentration | 200 ug/mL (prior to lyoph) |
| Purity | > 95% |
| Source | E.coli |
| Tag | N-terminal His Tag |
| Gene Symbol | Comp |
|---|---|
| Gene Full Name | cartilage oligomeric matrix protein |
| Alias Symbols | cartilage oligomeric matrix protein;thrombospondin-5;TS;TSP5. |
| NCBI Gene Id | 12845 |
| Protein Name | Cartilage oligomeric matrix protein |
| Description of Target | May play a role in the structural integrity of cartilage via its interaction with other extracellular matrix proteins such as the collagens and fibronectin. Can mediate the interaction of chondrocytes with the cartilage extracellular matrix through interaction with cell surface integrin receptors. Could play a role in the pathogenesis of osteoarthritis. Potent suppressor of apoptosis in both primary chondrocytes and transformed cells. Suppresses apoptosis by blocking the activation of caspase-3 and by inducing the IAP family of survival proteins (BIRC3, BIRC2, BIRC5 and XIAP). Essential for maintaining a vascular smooth muscle cells (VSMCs) contractile/differentiated phenotype under physiological and pathological stimuli. Maintains this phenotype of VSMCs by interacting with ITGA7 (By similarity). |
| Uniprot ID | Q9R0G6 |
| Protein Accession # | NP_057894.2 |
| Nucleotide Accession # | NM_016685.2 |
| Protein Size (# AA) | Thr40~Asn180 |
| Molecular Weight | 18kDa |