Human Calpain 2 (CAPN2) activation kit by CRISPRa

Referência GA100577

Tamanho : 1kit

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Human Calpain 2 (CAPN2) activation kit by CRISPRa

Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol CAPN2
Locus ID 824
Components

GA100577G1, Calpain 2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA100577G2, Calpain 2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA100577G3, Calpain 2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001146068, NM_001748
UniProt ID P17655
Synonyms CANP2; CANPL2; CANPml; mCANP
Summary The calpains, calcium-activated neutral proteases, are nonlysosomal, intracellular cysteine proteases. The mammalian calpains include ubiquitous, stomach-specific, and muscle-specific proteins. The ubiquitous enzymes consist of heterodimers with distinct large, catalytic subunits associated with a common small, regulatory subunit. This gene encodes the large subunit of the ubiquitous enzyme, calpain 2. Multiple heterogeneous transcriptional start sites in the 5' UTR have been reported. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
SKU Description Size
KN405642 CAPN2 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit

Citations

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