Human Monoacylglycerol Lipase (MGLL) activation kit by CRISPRa
Referência GA107810
Tamanho : 1kit
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Human Monoacylglycerol Lipase (MGLL) activation kit by CRISPRa
SKU
GA107810
MGLL CRISPRa kit - CRISPR gene activation of human monoglyceride lipase
2 Weeks*
| Product Data | |
| Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
|---|---|
| Target Symbol | MGLL |
| Locus ID | 11343 |
| Components | GA107810G1, Monoacylglycerol Lipase gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA107810G2, Monoacylglycerol Lipase gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA107810G3, Monoacylglycerol Lipase gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
| Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
| Reference Data | |
| RefSeq | NM_001003794, NM_001256585, NM_007283 |
| UniProt ID | Q99685 |
| Synonyms | HU-K5; HUK5; MAGL; MGL |
| Summary | This gene encodes a serine hydrolase of the AB hydrolase superfamily that catalyzes the conversion of monoacylglycerides to free fatty acids and glycerol. The encoded protein plays a critical role in several physiological processes including pain and nociperception through hydrolysis of the endocannabinoid 2-arachidonoylglycerol. Expression of this gene may play a role in cancer tumorigenesis and metastasis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2012] |
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| SDS |
| SKU | Description | Size | ||
|---|---|---|---|---|
| KN402412 | MGLL - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. | 1 kit | | |
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.