Mannose Receptor antibody [15-2] (PerCP-Cy5.5)
Referência GTX00491-11-100test
Tamanho : 100test
Marca : GeneTex
Host | Mouse |
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Clonality | Monoclonal |
Clone Name | 15-2 |
Isotype | IgG1 |
Application | ICC/IF, IHC-P, FACS |
Reactivity | Human, Mouse, Rat |
Package | 100 test |
View product citations for antibody GTX00491-11 on CiteAb
APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
Application | Recommended Dilution |
---|---|
ICC/IF | Assay dependent |
IHC-P | Assay dependent |
FACS | 4 μl reagent / 100 μl of whole blood or 10⁶ cells in a suspension |
Not tested in other applications.
PROPERTIES
Form
Liquid
Buffer
PBS
Preservative
15mM Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE. Protect from light.
Concentration
Batch dependent (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Purified human mannose receptor
Purification
Purified by size-exclusion chromatography
Conjugation
Peridinin-chlorophyll proteins-Cyanine5.5 (PerCP-Cy5.5)
Note
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption. Cy and CyDye are trademarks of GE Healthcare.
TARGET
Synonyms
CD206 , CLEC13D , CLEC13DL , MMR , MRC1 , MRC1L1 , bA541I19.1 , hMR , mannose receptor, C type 1 , Mannose Receptor , mrc1 , mannose receptor C-type 1
Cellular Localization
Endosome membrane,Cell membrane
Background
The recognition of complex carbohydrate structures on glycoproteins is an important part of several biological processes, including cell-cell recognition, serum glycoprotein turnover, and neutralization of pathogens. The protein encoded by this gene is a type I membrane receptor that mediates the endocytosis of glycoproteins by macrophages. The protein has been shown to bind high-mannose structures on the surface of potentially pathogenic viruses, bacteria, and fungi so that they can be neutralized by phagocytic engulfment.[provided by RefSeq, Sep 2015]
Database
Clone Reference
GH Han et al. Cell Prolif 2021; 54:e13050 Transplantation of tauroursodeoxycholic acid-inducing M2-phenotype macrophages promotes an anti-neuroinflammatory effect and functional recovery after spinal cord injury in rats
Application : ICC/IF, IHC-P, FACS
Reactivity : Rat
GK Katara et al. Oncogene 2014; 33 (49):5649-54 Tumor-associated vacuolar ATPase subunit promotes tumorigenic characteristics in macrophages
Application : ICC/IF
Reactivity : Human
PA Walker et al. J Neuroinflammation 2012; 9:228 Intravenous multipotent adult progenitor cell therapy after traumatic brain injury: modulation of the resident microglia population
Application : ICC/IF
Reactivity : Mouse
REVIEW
Clone Reference
GH Han et al. Cell Prolif 2021; 54:e13050 Transplantation of tauroursodeoxycholic acid-inducing M2-phenotype macrophages promotes an anti-neuroinflammatory effect and functional recovery after spinal cord injury in rats
Application : ICC/IF, IHC-P, FACS
Reactivity : Rat
GK Katara et al. Oncogene 2014; 33 (49):5649-54 Tumor-associated vacuolar ATPase subunit promotes tumorigenic characteristics in macrophages
Application : ICC/IF
Reactivity : Human
PA Walker et al. J Neuroinflammation 2012; 9:228 Intravenous multipotent adult progenitor cell therapy after traumatic brain injury: modulation of the resident microglia population
Application : ICC/IF
Reactivity : Mouse
SDS | |
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PBS.pdf | |
Sodium Azide.pdf |