BPS Bioscience
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BPS offers one of the largest selections of unique recombinant proteins and assay kits for epigenetic studies, immune checkpoints, metabolism and cell signaling pathways to improve human health.
Cloning and Expression: BPS Bioscience's Molecular Biology Services team can help you achieve any molecular biology research goal you are trying to achieve. Our gene cloning and site-directed mutagenesis services are often the first step in custom protein expression, analytic development, and custom cell line development projects.
Purification and Protein Modification: Choose BPS Bioscience for your protein, reduction, purification and modification needs. Using our cloning and expression services, the constructs can be optimized for high purity, high performance protein expression. We are also specialized in protein labeling to provide improved products for high quality testing.
Cell line development: Let our experts help you reduce time and complexity with our stable cell line development services. We produce customized cell lines for protein production and compound screening. Our specialty in reporter assays for immune control pathways offers great opportunities for research on co-immunotherapies.
Test Development and Screening Services: Evaluate key compounds with our biochemical and cell screening services. Save time by allowing us to filter your compounds of interest against our unique test panels or to determine IC50 values with our portfolio of hundreds of tests so you can focus on advancing your discovery program of drugs.
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Website: bpsbioscience.com
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In situ hybridization probes - Brain and neural pathology
There are 3 main types of brain and neural tumors.
A glioma is a type of tumor that starts in the brain or spine. It is called a glioma because it arises from glial cells. The most common site of gliomas is the brain. Gliomas make up about 30% of all brain and central nervous system tumors and 80% of all malignant brain tumors.
Neuroblastoma (NB) is the most common extracranial solid cancer in childhood and the most common cancer in infancy, with an incidence of about 650 cases per year in the U.S., and 100 cases per year in the UK. Nearly half of neuroblastoma cases occur in children younger than two years. It is a neuroendocrine tumor, arising from any neural crest element of the sympathetic nervous system (SNS). It most frequently originates in one of the adrenal glands, but can also develop in nerve tissues in the neck, chest, abdomen, or pelvis.
Glioblastoma multiforme (GBM), also known as glioblastoma and grade IV astrocytoma, is the most common and most aggressive cancer that begins within the brain. Signs and symptoms are initially non specific. They may include headaches, personality changes, nausea, and symptoms similar to that of a stroke. Worsening of symptoms is often rapid. This can progress to unconsciousness.
