BPS Bioscience

 

BPS offers one of the largest selections of unique recombinant proteins and assay kits for epigenetic studies, immune checkpoints, metabolism and cell signaling pathways to improve human health.
 
Cloning and Expression: BPS Bioscience's Molecular Biology Services team can help you achieve any molecular biology research goal you are trying to achieve. Our gene cloning and site-directed mutagenesis services are often the first step in custom protein expression, analytic development, and custom cell line development projects.
 
Purification and Protein Modification: Choose BPS Bioscience for your protein, reduction, purification and modification needs. Using our cloning and expression services, the constructs can be optimized for high purity, high performance protein expression. We are also specialized in protein labeling to provide improved products for high quality testing.
 
Cell line development: Let our experts help you reduce time and complexity with our stable cell line development services. We produce customized cell lines for protein production and compound screening. Our specialty in reporter assays for immune control pathways offers great opportunities for research on co-immunotherapies.
 
Test Development and Screening Services: Evaluate key compounds with our biochemical and cell screening services. Save time by allowing us to filter your compounds of interest against our unique test panels or to determine IC50 values ​​with our portfolio of hundreds of tests so you can focus on advancing your discovery program of drugs.
 

 

 Learn more :

 

  

 

 

 

             

Adoptive Cell Therapy 

  

Cell Systems For Drug Discovery

     

CRISPR-Cas9

 

DNA Damage Response

     

 

 

             

Epigenetics

 

Immunotherapy tools

 

Kinase Research Tools

       

Neurosciences

     

       

   
         
  Virus-Based Tools   Distributor Newsletter  

 

Watch the video :

 

 
 
         

Fluorescence Polarization Assays

 

    

Cell Systems for Drug Discovery

 

    

ONE-STEP Luciferase Assay System

BPS Bioscience

 

 

 
 
SARS-CoV-2 - Ruxolitinib - Therapeutic Candidates

SARS-CoV-2 - Ruxolitinib - Therapeutic Candidates


Ruxolitinib, whose commercial name is Jakavi, is a tyrosine kinase inhibitor and more specifically Janus kinase 1 (JAK1) and Janus kinase 2 (JAK2) which are JAK-targeting tyrosine kinases.  Ruxolitinib is used for the treatment of certain myeloproliferative syndromes such as myelofibrosis. It is also used for the treatment of Vaquez disease (essential polyglobulia or polycythemia vera or rubra), characterized by polyglobulia and an increase in total blood cell volume.
The Novartis group, which markets Jakavi, began studying the effects of this drug on Covid-19 caused by SARS-CoV-2. The purpose of this clinical study is to determine whether ruxolitinib could mitigate the potential complications of Covid-19 and involves patients with Covid-19-related cytokine shock. This Phase III clinical study is based on the fact that the JAK-STAT pathway is fundamental to many biological processes related to immunity and inflammation, including the mobilization of a cytokine response.

Resultado da sua pesquisa : 2 produto encontrado

Refine sua procura :

RUOCE / IVD
  • Unconjugated 2
  • human 1
  • Inhibitor/Antagonist/Agonist 2
  • human 1
APLICAR OS FILTROS
REINICIALIZAR


Referência
Descrição
Cond.
Price Bef. VAT
27059-1
 25mg 
27059-2
 100mg